Lab of Mesoscale Connectome Mapping - Publications

Publications

Highlights

(For a full list see below)

High-throughput mapping of a whole rhesus monkey brain at micrometer resolution

Here, We present an integrative approach that combines primate-optimized tissue sectioning and clearing with ultrahigh-speed, large-scale, volumetric fluorescence microscopy, capable of completing whole-brain imaging of a rhesus monkey at 1 µm × 1 µm × 2.5 µm voxel resolution within 100 hours.

Fang Xu, Yan Shen, Lufeng Ding, Chao-Yu Yang, Heng Tan, Hao Wang, Qingyuan Zhu, Rui Xu, Fengyi Wu, Yanyang Xiao, Cheng Xu, Qianwei Li, Peng Su, Li I. Zhang, Hong-Wei Dong, Robert Desimone, Fuqiang Xu, Xintian Hu, Pak-Ming Lau & Guo-Qiang Bi

Nature Biotechnology (2021)

 

Full List

Cross-modal coherent registration of whole mouse brains
Lei Qu, Yuanyuan Li, Peng Xie, Lijuan Liu, Yimin Wang, Jun Wu, Yu Liu, Tao Wang, Longfei Li, Kaixuan Guo, Wan Wan, Lei Ouyang, Feng Xiong, Anna C. Kolstad, Zhuhao Wu, Fang Xu, Yefeng Zheng, Hui Gong, Qingming Luo, Guoqiang Bi, Hongwei Dong, Michael Hawrylycz, Hongkui Zeng & Hanchuan Peng
Nature Methods (2021)

High-throughput mapping of a whole rhesus monkey brain at micrometer resolution
Fang Xu, Yan Shen, Lufeng Ding, Chao-Yu Yang, Heng Tan, Hao Wang, Qingyuan Zhu, Rui Xu, Fengyi Wu, Yanyang Xiao, Cheng Xu, Qianwei Li, Peng Su, Li I. Zhang, Hong-Wei Dong, Robert Desimone, Fuqiang Xu, Xintian Hu, Pak-Ming Lau & Guo-Qiang Bi
Nature Biotechnology (2021)

Scalable volumetric imaging for ultrahigh-speed brain mapping at synaptic resolution
Wang H, Zhu Q, Ding L, Shen Y, Yang CY, Xu F, Shu C, Guo Y, Xiong Z, Shan Q, Jia F. et.al.
National Science Review (2019)

Excitation wavelength optimization improves photostability of ASAP-family GEVIs
Fang Xu, Dong-Qing Shi, Pak-Ming Lau, Michael Z. Lin, Guo-Qiang Bi.
Molecular Brain (2018)

A cautionary tale of entropic criteria in assessing the validity of the maximum entropy principle
Zhi-Qin John Xu, Fang Xu, Guoqiang Bi, Douglas Zhou, David Cai
EPL (2019)

Continuous Dropout
Xu Shen, Xinmei Tian, Tongliang Liu, Fang Xu, Dacheng Tao
IEEE Transactions on Neural Networks and Learning Systems (2018)

Homeostatic regulation of spontaneous and evoked synaptic transmission in two steps
Richard C Gerkin, David W Nauen, Fang Xu, Guo-Qiang Bi
Molecular Brain (2013)